Sissification Vaccine

[UsuallyPresent]

Alternatively, switch the problem around. Make sissification the result of a virus (perhaps transmitted sexually).

Then people could work to find a cure/vaccine.

The infected men's cum could be the vector spreading the disease, perhaps?

Maybe women who have the immunization act as a carrier, possibly depending on their sexual dominance - the more dominant the woman the more likely they are to increase the effects in the men they fuck?