New Covid strain identified in Southern UK

WillJ8787

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Source:
https://www.healthline.com/health-news/why-you-shouldnt-freak-out-about-the-new-strain-of-covid-19

Definitely watching this.... hopefully, it's not significantly more virulent.

This is a significant danger with a already rapidly transmitting virus, that it will mutate towards a faster rate of transmission and with a higher mortality rate.

Here's to hoping and wanting these vaccinations to progress as fast as possible.

We are definitely not in control....mother nature always has the last and most significant word.
 
We are going into a new higher tier 4 lockdown from tomorrow morning...
 
Mutation is a function of probabilities. Think of it as a random event. A flip of the coin....will the virus get worse? Will it get better? 50:50. Now comes the fun part. When do mutations happen? That's right...as it replicates. So if it replicates more (more people)....the chances of a mutation event occurs increases. This is a secondary reason why masks were important. The less infections...the probability of a severe mutational event is reduced BY THE ORDER OF INFECTION RATE. So, if a country is experiencing an exponential rate of infections....guess what happens to the probability of a mutational event? It likewise, increases by a function of that exponential rate. Isn't statistics fucking wonderful?
 
Three weeks ago my local area had an infection rate of half the national average. Now we are at three times the national average.

Three weeks ago we had about a dozen people in hospital with covid. Now it is over 100.
 
Three weeks ago my local area had an infection rate of half the national average. Now we are at three times the national average.

Three weeks ago we had about a dozen people in hospital with covid. Now it is over 100.

Make sure you take to take care ogg. It is the high risk people that now have to deal with all the added risks
 
I'm sure the US vaccine covers ALL strains of the Covid. :rolleyes:
 
I'm sure the US vaccine covers ALL strains of the Covid. :rolleyes:

The Pfizer and Oxford Astra Zeneca vaccines do. As for the rest. Probably...

Except I wouldn't trust the Russian one...
 
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I'm sure the US vaccine covers ALL strains of the Covid. :rolleyes:

That isn't the issue. The issue is this strain has a higher rate of transmission and mortality. That means more people die. Once we get those that want to be vaccinated vaccinated ... then the mortality will only happen in those people that chose not to be vaccinated. I have no issue with them wanting to have a right to die....but they should pay for it...not those that choose to do the right things
 
That is comforting to know. That is the first I have heard they were. thankx

As long as a mutation does not occur in the protein coat of the virus...the part that the mRNA codes for, both the Pfizer and Moderna vaccines will remain effective. The Oxford vaccine will probably not be approved in the US because they had very serious design flaws in their testing methodology
 
That is comforting to know. That is the first I have heard they were. thankx

They are coded against an element of virus deemed essential to how it penetrates human cells. Changes in that protein would more likely make the virus less virulent than more, so those vaccines should be rather resilient to small variations of the virus. Besides if the mRNA vaccine technology is proven in Pfizer and Moderna vaccines, they at least theoretically can adjust it to new target proteins in matter of days (plus actual production and re-certification, of course).
 
I'm sure the US vaccine covers ALL strains of the Covid. :rolleyes:

Well that cuts out the Pfizer vaccine which was produced in Germany with German funding by Turkish immigrants.

Let's hear it for Islamic immigrants!
 
Source:
https://www.healthline.com/health-news/why-you-shouldnt-freak-out-about-the-new-strain-of-covid-19

Definitely watching this.... hopefully, it's not significantly more virulent.

This is a significant danger with a already rapidly transmitting virus, that it will mutate towards a faster rate of transmission and with a higher mortality rate.

Here's to hoping and wanting these vaccinations to progress as fast as possible.

We are definitely not in control....mother nature always has the last and most significant word.
so far there have been thousands of variants, mutations...and that's something perfectly normal in viruses due to how fast they replicate... but none that are causing concern in their behaviour. This one's different since it's showing signs of being able to spread faster. However, to date, I've not read anything that suggests mortality rates may change and mutations often result in less potent viruses. Still too early to know, but it's being studied; the fact we know about it is a good thing!

more here: https://virological.org/t/prelimina...defined-by-a-novel-set-of-spike-mutations/563
Summary
Recently a distinct phylogenetic cluster (named lineage B.1.1.7) was detected within the COG-UK surveillance dataset. This cluster has been growing rapidly over the past 4 weeks and since been observed in other UK locations, indicating further spread.

Several aspects of this cluster are noteworthy for epidemiological and biological reasons and we report preliminary findings below. In summary:

  • The B.1.1.7 lineage accounts for an increasing proportion of cases in parts of England. The number of B.1.1.7 cases, and the number of regions reporting B.1.1.7 infections, are growing.
  • B.1.1.7 has an unusually large number of genetic changes, particularly in the spike protein.

Three of these mutations have potential biological effects that have been described previously to varying extents:

Mutation N501Y is one of six key contact residues within the receptor-binding domain (RBD) and has been identified as increasing binding affinity to human and murine ACE2.
The spike deletion 69-70del has been described in the context of evasion to the human immune response but has also occurred a number of times in association with other RBD changes.
Mutation P681H is immediately adjacent to the furin cleavage site, a known location of biological significance.

The rapid growth of this lineage indicates the need for enhanced genomic and epidemiological surveillance worldwide and laboratory investigations of antigenicity and infectivity.
 
so far there have been thousands of variants, mutations...and that's something perfectly normal in viruses due to how fast they replicate... but none that are causing concern in their behaviour. This one's different since it's showing signs of being able to spread faster. However, to date, I've not read anything that suggests mortality rates may change and mutations often result in less potent viruses. Still too early to know, but it's being studied; the fact we know about it is a good thing!

more here:

Mortality is not just a function of the virus. It is a function of both the virus AND our ability to handle it. If you have a full ICU staff and 6 sick people in beds...or 30 sick people...which group would you expect to get better care? Those that can get 10 minutes of attention from each employee per hour? Or those that get 2 minutes per hour? What happens if one patient goes into arrest? Do the others get the same attention? Mortality is increasing and statistically, it is a confounded variable....making it impossible to identify if the virus has become more lethal or if the increased mortality is a result of overworked staff incapable of doing the job they want to do. Either way...more people are dying now. We are not witnessing a linear function of loss of life
 
Source:
https://www.healthline.com/health-news/why-you-shouldnt-freak-out-about-the-new-strain-of-covid-19

Definitely watching this.... hopefully, it's not significantly more virulent.

This is a significant danger with a already rapidly transmitting virus, that it will mutate towards a faster rate of transmission and with a higher mortality rate.

Here's to hoping and wanting these vaccinations to progress as fast as possible.

We are definitely not in control....mother nature always has the last and most significant word.

u like political lockdown
now do the flu
 
Mortality is not just a function of the virus. It is a function of both the virus AND our ability to handle it. If you have a full ICU staff and 6 sick people in beds...or 30 sick people...which group would you expect to get better care? Those that can get 10 minutes of attention from each employee per hour? Or those that get 2 minutes per hour? What happens if one patient goes into arrest? Do the others get the same attention? Mortality is increasing and statistically, it is a confounded variable....making it impossible to identify if the virus has become more lethal or if the increased mortality is a result of overworked staff incapable of doing the job they want to do. Either way...more people are dying now. We are not witnessing a linear function of loss of life

i saw on the news a death that was not attributed to cancer
u would never say it was a cold
follow the benjamins
 
Mortality is not just a function of the virus. It is a function of both the virus AND our ability to handle it. If you have a full ICU staff and 6 sick people in beds...or 30 sick people...which group would you expect to get better care? Those that can get 10 minutes of attention from each employee per hour? Or those that get 2 minutes per hour? What happens if one patient goes into arrest? Do the others get the same attention? Mortality is increasing and statistically, it is a confounded variable....making it impossible to identify if the virus has become more lethal or if the increased mortality is a result of overworked staff incapable of doing the job they want to do. Either way...more people are dying now. We are not witnessing a linear function of loss of life
oh, i completely agree with all of the above; my point was that i read what will stated as the new variant is more virulent in its effects... and i don't think science is showing us that, just yet. given its ability to spread more easily, and faster, we can only hope it isn't more deadly! the fact that is IS recognised and being studied is good news in this ongoing war.

speaking of which i watched a cnn documentary last night on the 1918 flu pandemic; so much of the behaviours back then in the states, both political and population-wise, has been mirrored this time around... from woodrow wilson NEVER commenting on it at all (and others in power playing it down as much as possible) because they wanted people to focus elsewhere (the war), to some states closing early but relaxing and reopening too soon leading to a massive hike in deaths. The first wave wasn't so bad for a lot of people, which led certain sections of the population to be up in arms against mask mandates when the second, deadlier, wave hit the u.s. It's like nothing was learned, or too much forgotten. :(
 
A "CNN documentary"? Thats the most hilarious oxymoron I've heard in weeks. Thanks, I needed that. Good one! :D
 
One of the big risks involved in allowing a viral pandemic to get out of control is it increases the probability of mutation. We already knew about the risk to overloading health care facilities and incurring excessive deaths, but the more people who are infected, the more opportunities there are for viral mutation to take place.

For all those know-it-alls who undermined public health measures during the past year and who promoted "freedom to infect" and foolish theories about the need to let the virus do its thing in order to reach a faster herd immunity, your irresponsibility is resulting in very high costs right now.
 
The previous mutation was more contagious, but possibly less lethal. That's not an uncommon pattern.
 
The previous mutation was more contagious, but possibly less lethal. That's not an uncommon pattern.

Lethality does tend to decrease with time. This is a statistical process associated with combinatorial genetics. What i am saying is a dead person is a dead person. It does not matter if the virus is less lethal if more people have it. You still overload the health care system. THAT is what kills more people. Always look at the weak link
 
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