Covid Booster Shot Hopes & Prayers

BabyBoomer50s

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Michael Mina, Harvard Public Health/Medical School epidemiologist, immunologist, physician, raises a good point on Twitter today.

“Anyone else frustrated that boosters will be the original vaccine? The power of mRNA vaccines is that they can be adapted quickly.

“Why push for a vaccine that is already outdated. If we are going to boost - use a delta variant of the vaccine. Delta is our baseline now.

“And for that matter - any vaccines moving forward should begin to incorporate Delta (and other/future) relevant mutations. We can accelerate review of minor changes without full efficacy trials.”
 
Michael Mina, Harvard Public Health/Medical School epidemiologist, immunologist, physician, raises a good point on Twitter today.

“Anyone else frustrated that boosters will be the original vaccine? The power of mRNA vaccines is that they can be adapted quickly.

“Why push for a vaccine that is already outdated. If we are going to boost - use a delta variant of the vaccine. Delta is our baseline now.

“And for that matter - any vaccines moving forward should begin to incorporate Delta (and other/future) relevant mutations. We can accelerate review of minor changes without full efficacy trials.”

If the original vaccine is effective, there's no reason to redevelop it. Adding that redeveloping would require another year to trial and probably one more for approval

I'd guess that they will develop a second vaccine to be used in future vaccinations
 
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Um, because the current iteration of the vaccines have shown to be quite effective against Delta when it comes to serious illness, hospitalization, and death??? Of course when you're unvaccinated those points are irrelevant.

The recent report that the J&J "booster" increases Covid antibodies 9X is fairly relevant and encouraging as well

There is also a cost component and a supply component to consider.

Also, would new iterations of the vaccines require additional FDA approval???

If that is the case, then the anti-vaxxers would have another excuse to refuse to get vaccinated.

Hope that helps

:D
 
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Um, because the current iteration of the vaccines have shown to be quite effective against Delta when it comes to serious illness, hospitalization, and death??? Of course when you're unvaccinated those points are irrelevant.

The recent report that the J&J "booster" increases Covid antibodies 9X is fairly relevant and encouraging as well

There is also a cost component and a supply component to consider.

Also, would new iterations of the vaccines require additional FDA approval???

If that is the case, then the anti-vaxxers would have another excuse to refuse to get vaccinated.

Hope that helps

:D

1. Nobody said the vaccines don’t help reduce severity of symptoms, even against Delta
2. The vaccines are not so good at reducing transmission, especially bad against the Delta variant.
3. The vaccines have only been in widespread use since December. About 8 months. We’re already talking about waning effectiveness that nobody predicted. We had no idea. Now, with most people less than 8 months into their vaccinations, someone knows how that’s gonna work out? How many people who got vaccinated 8 months ago are in the trials? How many by age and risk category? How long have the trials been running? Long enough to show the booster works 6 months later? A year? 3 years? This a new, untested protocol. It’s like adding a little more catsup on your French fries.
 
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The recent report that the J&J "booster" increases Covid antibodies 9X is fairly relevant and encouraging as well

I got the J&J, and I think this, which I also read today, addresses the OP assertion on this vaccine.
 
1. Nobody said the vaccines don’t help reduce severity of symptoms, even against Delta
2. The vaccines are not so good at reducing transmission, especially bad against the Delta variant.
3. The vaccines have only been in widespread use since December. About 8 months. We’re already talking about waning effectiveness that nobody predicted. We had no idea. Now, with most people less than 8 months into their vaccinations, someone knows how that’s gonna work out? How many people who got vaccinated 8 months ago are in the trials? How many by age and risk category? How long have the trials been running? Long enough to show the booster works 6 months later? A year? 3 years? This a new, untested protocol. It’s like adding a little more catsup on your French fries.
2. Yes, vaccines will reduce transmission of Covid19, including the Delta variant. A vaccinated person with a robust immune system will rarely become infected and spread the virus to others.
3. There are a lot of people who don’t have robust immune systems for a variety of reasons, and boosters can pick up that slack. For some, the original vaccine’s protection might last a few months, for others it will last for years.
 
The vaccines are very good at reducing the incidence of death by Covid. Anyone who doesn't understand and appreciate this--and isn't motivated to be vaccinated--is dumb as a rock and their relative health insurance premiums should reflect this.
 
The vaccines are very good at reducing the incidence of death by Covid. Anyone who doesn't understand and appreciate this--and isn't motivated to be vaccinated--is dumb as a rock and their relative health insurance premiums should reflect this.

As soon as they and you, start doing the same for people who are obese and or smoke ciggs, which would be RACIST!!!! and Trump level white supremacy, I'll take you and that retarded opinion of yours somewhat seriously.
 
1. Nobody said the vaccines don’t help reduce severity of symptoms, even against Delta
2. The vaccines are not so good at reducing transmission, especially bad against the Delta variant.
3. The vaccines have only been in widespread use since December. About 8 months. We’re already talking about waning effectiveness that nobody predicted. We had no idea. Now, with most people less than 8 months into their vaccinations, someone knows how that’s gonna work out? How many people who got vaccinated 8 months ago are in the trials? How many by age and risk category? How long have the trials been running? Long enough to show the booster works 6 months later? A year? 3 years? This a new, untested protocol. It’s like adding a little more catsup on your French fries.

2. It's actually quite good at reducing transmission with Delta. The problem is that the transmission rate is incredibly high for Delta, which makes it appear to be not effective at all.
3. Nobody predicted what they had no data for. And Delta was new, so even less data.

You keep comparing strains and conflating the information regarding them. We only have data regarding Delta since late 2020.
 
The vaccines are very good at reducing the incidence of death by Covid. Anyone who doesn't understand and appreciate this--and isn't motivated to be vaccinated--is dumb as a rock and their relative health insurance premiums should reflect this.

Nobody said they didn’t reduce severity of symptoms, including hospitalization and death. Unfortunately they don’t reduce the chances very long. Nobody saw that coming either. Now we’re being told after just 6 to 8 months you might need a booster. How long that booster lasts? Nobody knows.

And as Michael Mina notes, the current mRNA vaccines are not very effective at reducing transmission which is why it’s foolish to not use a modified booster that works better against Delta. Breakthrough infections are very common and viral loads of vaccinated people are comparable to those of unvaccinated people. That’s why public health agencies are telling you to mask up even if you’re vaccinated.
 
2. It's actually quite good at reducing transmission with Delta. The problem is that the transmission rate is incredibly high for Delta, which makes it appear to be not effective at all.
3. Nobody predicted what they had no data for. And Delta was new, so even less data.

You keep comparing strains and conflating the information regarding them. We only have data regarding Delta since late 2020.

You’re supporting Dr. Mina’s point. The current vaccines don’t work well at reducing transmission of Delta. Why push a vaccine that’s already outdated?
 
Michael Mina, Harvard Public Health/Medical School epidemiologist, immunologist, physician, raises a good point on Twitter today.

“Anyone else frustrated that boosters will be the original vaccine? The power of mRNA vaccines is that they can be adapted quickly.

“Why push for a vaccine that is already outdated. If we are going to boost - use a delta variant of the vaccine. Delta is our baseline now.

“And for that matter - any vaccines moving forward should begin to incorporate Delta (and other/future) relevant mutations. We can accelerate review of minor changes without full efficacy trials.”

It's going to be a bit of a whack-a-mole game with variants, and any modifications to the mRNA vaccines will need to have some safety testing.

However, I think from a clinical perspective, boosters of the original vaccines will prove to be helpful. I'd like to see more discussion of heterologous (mixing and matching vaccine types) for boosters; I think they may have the potential to show some synergy.

There are at least 93 COVID-19 vaccines currently in development, so potentially some of them will be more efficacious against the Delta variant (or whatever variant pops up next). It would be great to have a large arsenal of vaccines as well as some kind of easy way of knowing (without doing efficacy studies) which might be most effective against new variants.
 
As soon as they and you, start doing the same for people who are obese and or smoke ciggs, which would be RACIST!!!! and Trump level white supremacy, I'll take you and that retarded opinion of yours somewhat seriously.

Insurance premiums ARE higher for those who are morbidly obese and/or smoke. Don't know much, do you?

I obviously hit a sensitive note with your ignorance. :D
 
Nobody said they didn’t reduce severity of symptoms, including hospitalization and death. Unfortunately they don’t reduce the chances very long.

You don't know that. We haven't been into this long enough for that to be anything but your divisive opinion.
 
The point of ensuring there weren't variants was for everyone who could get the vaccine to do so responsibly for the good all and nip this in the bud before there could be variants. But the uwashed ignorant, egged on by the board Trumpettes have prevented this from happening.
 
You don't know that. We haven't been into this long enough for that to be anything but your divisive opinion.

Lol. Maybe you should have a little talk with the CDC, the Surgeon General, President Biden, and of course St. Fauci about their “divisive opinions.” They’re the ones talking about waning efficacy and the need for booster shots.
 
Lol. Maybe you should have a little talk with the CDC, the Surgeon General, President Biden, and of course St. Fauci about their “divisive opinions.” They’re the ones talking about waning efficacy and the need for booster shots.

False equivalency in the largest sense of the term.

Biden and the CDC are talking about the best way for Americans to protect themselves and their family.

Antivaxxers are using discussion of waning efficacy and booster shots to discourage morons from getting the vaccine because they're morons who are afraid of medical advancements and science (and in many cases because of their God who hates science)
 
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