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I think that a big part of a marriage surviving serious sexual dysfunction hinges less on the question "Does she want sex?" and more on the question "Does she think that sex is an important part of your marriage?" The former is a state of being caused by any number of issues, including the medications that she's taking. The later is a state of mind, and an understanding of the potential that this situation has for breaking down intimacy in her marriage and eventually the marriage itself. It sounds like you are already part way there.
My advice comes in two parts. First, ask her her opinion about the importance of sex in your marriage. If she intuitively understands that it's important, then ask her to consider going to her Dr to do something about the meds. Changing meds may not do anything, but it will be a start. If she is also on hormonal birth control, then also look into the effect that it has on women's libido and consider switching to condoms, getting a vasectomy, or something non-hormonal to give her body a fighting chance at wanting sex. If she doesn't think that it's important, then you need to convey that it is important to you and that without it you are left feeling disconnected and isolated from her, and you need to express how that makes you feel. While you need to have empathy for your wife's situation, it is your job to express your concerns if the marriage is suffering.
Second, I would suggest that you take a look at how sleeping in separate beds is contributing to the way that you are feeling about your wife. If you are in separate beds for health or schedule reasons, you may need to make some adjustments to allow yourselves the opportunity to connect sexually. If you are in separate beds for no other reason than not wanting to sleep with a woman who is sexually unresponsive, then you need to consider how that is compounding the situation and contributing to your feelings. Sleeping in the same bed creates the opportunity for the intimacy of saying good night and good morning to each other, and physical intimacy that doesn't lead to sex such as spooning and affectionate touching. I have been in the position of frustration when physical closeness and intimacy lead to wanting to have sex, only to have been rejected sexually and I know that it sucks.
If your wife understands that you need sexual intimacy and is willing to make an effort, then you at least have someplace to start. Being an understanding and compassionate spouse goes both ways. You need to understand her situation and needs, and she needs to understand yours. If the situation eventually wears down your marriage to the point where it breaks apart, then you have everything to gain and nothing to lose by trying to find some middle ground.
Best to you both.